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A Feasibility Study of routine Gastric residual volume measurement in mechanically ventilated Infants and Children: the GASTRIC

GASTRIC

A Feasibility Study of routine Gastric residual volume measurement in mechanically ventilated Infants and Children: the GASTRIC
Funding NIHR HTA
Portfolio Paediatric, foetal and maternal health
Interventions Other
Randomised No
Status Analysis/reporting
Start Date 18-Apr-2017

The aim of this study was to see if it is possible to conduct a large trial across the UK of not measuring the stomach contents (gastric residual volume or GRV) to guide the feeding of sick babies and children. It is a mixed methods study with 5 interlinked work packages:
1) An online survey was sent via national research networks to health professionals in paediatric intensive care units and neonatal units. The survey asked health professionals about current practice.
2) Qualitative semi-structured interviews were held with parents of children who have experience of mechanical ventilation and tube feeding in a paediatric intensive care unit and neonatal unit, and semi-structured interviews and focus groups were held with health professionals.
3) A second online survey including a Delphi study was sent to health professionals and asked questions about trial design issues including willingness to randomise and inclusion and exclusion criteria. The aim of the Delphi aspect of the survey was to obtain consensus from health professionals regarding outcomes for a future trial.
4) The National Neonatal Research Database and Paediatric Intensive Care Audit Network were analysed to determine the potential eligible population and numbers for a future trial based on inclusion and exclusion criteria determined in the above online survey.
5) A face-to-face consensus meeting was held to bring together key stakeholders to obtain feedback on preliminary results and to assess the ‘acceptability’ of a future trial. Any outcomes that failed to reach consensus in the Delphi aspect of the above survey were voted on again during this meeting.

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