|Funding||Department of Health|
People with diabetes are at risk of developing diabetic retinopathy which could lead to a loss of vision. The risk is different for each person based on factors such as type of diabetes, blood pressure and diabetes control. Currently in England all people with diabetes are invited for photographic eye screening once a year as part of the National Diabetic Eye Screening Programme. Screening aims to detect eye changes which may soon affect the vision so that the person can be referred to the Hospital Eye Service for close monitoring and treatment. In this way the risk of losing vision can be reduced. However, there is evidence that not everyone needs to be screened every year because the chances of them developing eye changes are low. Also, there are some people who are at high risk and would benefit from screening more frequently.
The ISDR study is the first randomised trial of personalised risk-based screening for Diabetic Retinopathy. Patients aged 12 years and over with diabetes registered with a GP whose postcode is in the city boundaries of Liverpool and attending for screening for diabetic retinopathy were invited to enter the trial. Patients were randomised to either individualised risk-based screening recall (6, 12 or 24 months) or annual screening. The study Closed to recruitment in June 2016, randomising 4538 patients over 19 months and this will provide data on safety, cost-effectiveness and acceptability of risk-based Diabetic Retinopathy screening in the UK.