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STRIDER

A Randomized Controlled Trial of Sildenafil Therapy In Dismal Prognosis Early-Onset Intrauterine Growth Restriction

STRIDER

A Randomized Controlled Trial of Sildenafil Therapy In Dismal Prognosis Early-Onset Intrauterine Growth Restriction
Funding NIHR EME
Portfolio Paediatric, foetal and maternal health
Interventions Medicine
Randomised Yes
Status Closed
Start Date 06-Nov-2014

Strider UK is a randomised controlled trial examaning the effect of the drug sildenafil versus placebo on keeping babies (who are severley growth restricted) inside the mother's womb for longer. This trial was conducted in 19 expert fetal medicine centres within the UK.

Publications

  • Groom, K. M., Ganzevoort, W., Alfirevic, Z., Lim, K., & Papageorghiou, A. T. (2018). doi:10.1002/uog.19186 Groom, K. M., Ganzevoort, W., Alfirevic, Z., Lim, K., & Papageorghiou, A. T. (2019). doi:10.1002/uog.20202 Kenny, L. C., Alfirevic, Z., Baker, P. N., Ganzevoort, W., Gluud, C., Groom, K. M., . . . von Dadelszen, P. (2018). doi:10.1136/bmj.k4872 Khalil, A., Sharp, A., Cornforth, C., Jackson, R., Mousa, H., Stock, S., . . . Alfirevic, Z. (2019). doi:10.1002/uog.20851 Pels, A., Kenny, L. C., Alfirevic, Z., Baker, P. N., von Dadelszen, P., Gluud, C., . . . Groom, K. M. (2017). doi:10.1186/s12884-017-1594-z Sharp, A., Cornforth, C., Jackson, R., Harrold, J., Turner, M. A., Kenny, L., . . . Alfirevic, Z. (2019). doi:10.1016/s2352-4642(19)30020-3 Sharp, A., Cornforth, C., Jackson, R., Harrold, J., Turner, M. A., Kenny, L. C., . . . Alfirevic, Z. (2018). doi:10.1016/s2352-4642(17)30173-6 Sharp, A., Jackson, R., Cornforth, C., Harrold, J., Turner, M. A., Kenny, L., . . . Alfirevic, Z. (2019). doi:10.1016/j.ejogrb.2019.08.007
    1. https://doi.org/10.1016/S2352-4642(19)30020-3