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TITAN

Trial of Induction TPF Therapy in Advanced Head & Neck Cancer.

TITAN

Trial of Induction TPF Therapy in Advanced Head & Neck Cancer.
Funding CR:UK
Portfolio Cancer
Interventions Medicine
Randomised Yes
Status Closed
Start Date 02-Nov-2011

TITAN is a open-label randomized controlled trial conducted in patients with previously untreated locally advanced head and neck squamous cell carcinoma (HNSCC).

Induction(TPF) chemotherapy is a significant recent advance in the management of locally advanced HNSCC, although its use in combination with Surgery and postoperative radiotherapy(PORT) is under-researched.

TITAN address the potential survival advantage of TPF induction chemotherapy prior to Surgery and radiotherapy for locally advanced resectable SCCHN.